Neomycin and Fluocinolone

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Cream, External: Neomycin sulfate 0.5% and fluocinolone acetonide 0.025% (15 g, 60 g)

Neomycin interferes with bacterial protein synthesis by binding to 30S ribosomal subunits.

Topical corticosteroids have anti-inflammatory, antipruritic, and vasoconstrictive properties. May depress the formation, release, and activity of endogenous chemical mediators of inflammation (kinins, histamine, liposomal enzymes, prostaglandins) through the induction of phospholipase A2 inhibitory proteins (lipocortins) and sequential inhibition of the release of arachidonic acid. Fluocinolone has low to intermediate range potency (dosage-form dependent).

Note: Dosage should be based on severity of disease and patient response; use smallest amount for shortest period of time. Therapy should be discontinued when control is achieved.

Corticosteroid-responsive dermatoses: Topical: Apply a thin film to affected area 2 to 4 times daily depending on severity of condition.

Topical: For external use only; not for oral use. Unless otherwise directed by healthcare professional, do not use with occlusive dressing; do not use on children's skin covered by diapers or plastic pants.

Store between 15°C and 25°C (59°F and 77°F); avoid freezing and excessive heat above 40°C (104°F).

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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