Mst

Do not use magnesium salicylate just before or after heart bypass surgery (coronary artery bypass graft, or CABG). You should not use this medication if you are allergic to aspirin or to an NSAID (non-steroidal anti-inflammatory drug), or if you have recently used:

• cidofovir (Vistide); or

• ketorolac (Toradol).

Magnesium salicylate may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

Magnesium salicylate may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking this medicine, especially in older adults.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

• kidney disease;

• asthma;

• heart disease, high blood pressure, congestive heart failure;

• a history of stroke or heart attack;

• a stomach ulcer or intestinal bleeding;

• a bleeding or blood clotting disorder;

• diabetes;

• swelling or fluid retention;

• anemia (a lack of red blood cells);

• liver disease;

• an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

• nasal polyps; or

• if you are dehydrated.

FDA pregnancy category C. Magnesium salicylate may be harmful to an unborn baby if the mother takes the medication during the last 3 months of pregnancy. Do not take this medication without telling your doctor if you are pregnant or plan to become pregnant during treatment.

Magnesium salicylate can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Salicylates can cause a serious and sometimes fatal condition called Reye's syndrome in children.

Older adults may be more likely to have side effects from magnesium salicylate.

Since magnesium salicylate is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

If you also take an antibiotic, avoid taking it within 2 hours before or after you take magnesium salicylate. This medication can make it harder for your body to absorb certain antibiotics.

Ask a doctor or pharmacist before using any other over-the-counter medication. Salicylates and NSAIDs are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains aspirin, ibuprofen, naproxen, ketoprofen, magnesium salicylate, or similar medicines.

If you are also taking low-dose aspirin because your doctor has prescribed it to prevent heart attack or stroke, do not stop taking it or change your dose without your doctor's advice. Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Avoid smoking, since it can also increase your risk of stomach bleeding.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
• Very bad belly pain.
• Feeling confused.
• Ringing in ears.
• Hearing loss.

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Belly pain or heartburn.
• Upset stomach or throwing up.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Some side effects of MST may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.