Montelukast Oral Tablet

Name: Montelukast Oral Tablet

Highlights for montelukast

Montelukast is used to prevent and treat symptoms of asthma and seasonal or year-round allergies. Montelukast tablets and chewable tablets can also be used to prevent tightening of the airways from exercise. This is called exercise-induced bronchoconstriction (EIB).

Montelukast comes in the form of a tablet that can be swallowed whole, or as a chewable tablet. It’s also available as granules that can be dissolved in liquid or soft food.

All forms of montelukast are available as a brand-name drug called Singulair. They’re also available as generic drugs.

The more common side effects of this drug can include fever, headache, sore throat, cough, stomach pain, runny nose, or diarrhea.

Montelukast should not be used in place of inhaled or oral corticosteroids for moderate, persistent asthma with daily symptoms. If you take corticosteroids, you can take these drugs together.

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What is montelukast?

Montelukast is a prescription drug. It’s available as a tablet that can be swallowed whole, or as a chewable tablet. It’s also available as granules that can be dissolved in liquid or soft food.

All forms of montelukast are available as a brand-name drug called Singulair. They’re also available as generic drugs. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version. Talk to your doctor to see if the generic version will work for you.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

Montelukast is used to prevent and treat asthma. It’s also used to treat seasonal and year-round allergies.

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How it works

Montelukast belongs to a class of drugs called leukotriene receptor antagonists.

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Montelukast Side Effects

More Common Side Effects

The more common side effects that can occur with use of montelukast include:

  • upper respiratory infection (infection in the nose or throat)

  • fever

  • headache

  • sore throat

  • cough

  • stomach pain

  • diarrhea

  • earache or ear infection

  • flu

  • runny nose

  • sinus infection

  • bed-wetting in children

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Behavior and mood changes. Symptoms can include:

    • feeling anxious
    • bad or vivid dreams
    • confusion
    • agitation
    • restlessness
    • tremor
    • trouble sleeping
  • Increase in eosinophils (white blood cells)

  • Systemic vasculitis (inflamed blood vessels). Symptoms can include:

    • feeling of “pins and needles” or numbness in the arms or legs
    • flu-like symptoms such as fever, muscle aches, or cold sweats
    • severe pain and swelling of the sinuses
  • Increased bleeding. Symptoms can include:

    • bleeding under the skin
    • longer bleeding from cuts
    • blood in the urine or feces
  • Stevens-Johnson syndrome. This is a medical emergency. Symptoms can include:

    • swelling of the face or tongue
    • hives
    • skin pain
    • a purple or red rash
  • Uncontrolled muscle movements. Symptoms can include:

    • tics (muscle spasms)
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Montelukast May Interact with Other Medications

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.

To find out how montelukast might interact with something else you’re taking, talk to your doctor or pharmacist.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Drug warnings

People with aspirin or NSAID allergy

If you have a sensitivity or allergy to aspirin or non-steroidal anti-inflammatory drugs (NSAIDs), you should continue to avoid these drugs while taking this drug. Sensitivity to these drugs may lead to tightening of your airways, and this drug may not fully treat these symptoms.

Pregnant women

This drug is a category B pregnancy drug. That means two things:

  1. Studies of the drug in pregnant animals have not shown a risk to the fetus.
  2. There aren’t enough studies done in pregnant women to show if the drug poses a risk to the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk to the fetus.

Women who are breast-feeding

It is not known if this drug passes into breast milk or causes side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your child. You may need to decide whether to stop breast-feeding or stop taking this medication.

For seniors

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

When to call the doctor

Go to the emergency room if you have an asthma attack that is not relieved by using a rescue inhaler. Early signs of an asthma attack include cough, wheezing, losing your breath easily, or feeling short of breath. They also include feeling tired, having trouble sleeping, or having allergy symptoms (such as sneezing, runny nose, nasal congestion, or headache).

Call your doctor if you become pregnant while taking this drug.

Allergies

This drug can cause a severe allergic reaction. Symptoms can include:

  • swelling of the face, lips, tongue, and/or throat
  • trouble breathing
  • hives
  • itching

If you have a reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

How to Take montelukast (Dosage)

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Asthma

Brand: Singulair

Form: Oral tablet Strengths: 10 mg

Generic: montelukast

Form: Oral tablet Strengths: 10 mg Adult dosage (ages 18 years and older)
  • The typical dosage is one 10-mg tablet taken once daily in the evening.
Child dosage (ages 15–17 years)
  • The typical dosage is one 10-mg tablet taken once daily in the evening.
Child dosage (ages 0–14 years)
  • The use of montelukast tablets has not been studied in children younger than 15 years.
Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

If you have both asthma and allergic rhinitis, you should take only one dose of montelukast daily in the evening.

If you’re already taking montelukast for asthma or allergies, you should not take an extra dose to prevent EIB.

Allergic rhinitis (seasonal and perennial)

Brand: Singulair

Form: Oral tablet Strengths: 10 mg

Generic: montelukast

Form: Oral tablet Strengths: 10 mg Adult dosage (ages 18 years and older)
  • The typical dosage is one 10-mg tablet taken once daily in the evening. 
Child dosage (ages 15–17 years)
  • The typical dosage is one 10-mg tablet taken once daily.
Child dosage (ages 0–14 years)
  • The use of montelukast tablets has not been studied in children younger than 15 years.
Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

If you have both asthma and allergic rhinitis, you should take only one dose of montelukast daily in the evening.

If you’re already taking montelukast for asthma or allergies, you should not take an extra dose to prevent EIB.

Exercise-induced bronchoconstriction (EIB)

Brand: Singulair

Form: Oral tablet Strengths: 10 mg

Generic: montelukast

Form: Oral tablet Strengths: 10 mg Adult dosage (ages 18 years and older)
  •   The typical dosage is one 10-mg tablet taken 2 hours before exercise.
Child dosage (ages 15–17 years)
  • The typical dosage is one 10-mg tablet taken 2 hours before exercise.
Child dosage (ages 0–14 years)
  • The use of montelukast tablets has not been studied in children younger than 15 years.
Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

 Warnings

If you have both asthma and allergic rhinitis, you should take only one dose of montelukast daily in the evening.

If you’re already taking montelukast for asthma or allergies, you should not take an extra dose to prevent EIB.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you. Important considerations for taking this drug

You can take this drug with or without food. Taking it with food may help to reduce upset stomach.

Take this drug at the time(s) recommended by your doctor

Do not cut or crush the tablet

Store this drug carefully

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A prescription for this medication is refillable

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Travel

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Self-management

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Clinical monitoring

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Insurance

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Are there any alternatives?

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