MitoMYcin (Ophthalmic)

Name: MitoMYcin (Ophthalmic)




Women who are or may become pregnant during therapy


Cytotoxic agent; use in concentrations >0.2 mg/mL or use for longer than 2 minutes may lead to unintended corneal and/or scleral damage including thinning or perforation

Direct contact with the corneal endothelium will result in cell death

Associated with an increased instance of postoperative hypotony

Use in phakic patients has been correlated to a higher instance of lenticular change and cataract formation

What do I need to tell my doctor BEFORE I take MitoMYcin?

  • If you have an allergy to mitomycin or any other part of mitoMYcin (ophthalmic).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are pregnant or may be pregnant. Do not use this medicine if you are pregnant.
  • If you are breast-feeding or plan to breast-feed.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take mitoMYcin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out MitoMYcin?

  • If you need to store this medicine at home, talk with your doctor, nurse, or pharmacist about how to store it.


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Dosing Adult

Glaucoma surgery (adjunctive therapy): Topical ophthalmic: 0.2 mg solution is aseptically applied via saturated sponges to surgical site of glaucoma filtration surgery for 2 minutes

Dosing Renal Impairment

There are no dosage adjustments provided in the manufacturer’s labeling.


For aseptic topical administration to surgical site of glaucoma filtration surgery; not for intraocular administration. The inner tray and the contents of the kit are sterile and should only be handled, opened and assembled by a sterile surgical scrub technician. Use within 1 hour of reconstitution. Technician should fully saturate sponges provided in the kit with the entire reconstituted solution (0.2 mg). Allow saturated sponges to remain undisturbed in kit for 60 seconds. Saturated sponges should be applied aseptically with the use of surgical forceps in a single layer to a treatment area ~10 mm × 6 mm (± 2 mm); sponges should be removed from the treatment area after 2 minutes. Following removal of sponges from eye, the surgical site should be copiously irrigated. Saturated sponges should be returned to the provided tray for disposal into chemotherapy waste bag. Consult product labeling for additional details.

What should I avoid after receiving mitomycin ophthalmic?

Do not use other eye medications unless your doctor tells you to.


Consult your pharmacist.