Meropenem and Vaborbactam Injection

Meropenem and vaborbactam injection is used to treat serious urinary tract infections, including kidney infections, that are caused by bacteria. Meropenem is in a class of medications called carbapenem antibiotics. It works by killing bacteria. Vaborbactam is in a class of medications called beta-lactamase inhibitors. It works by preventing bacteria from destroying meropenem.

Antibiotics such as meropenem and vaborbactam injection will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Unless your doctor tells you otherwise, continue your normal diet.

Meropenem and vaborbactam injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

1. headache
2. diarrhea
3. nausea
4. redness, pain, or swelling at the injection site
5. burning or tingling in the hands or feet
6. confusion

Some side effects can be serious. If you experience any of these symptoms, stop using meropenem and vaborbactam injection and call your doctor immediately or get emergency medical treatment:

1. seizures
2. hives
3. itching
4. rash
5. flushing
6. swelling of the face, throat, tongue, lips, and eyes
7. difficulty swallowing or breathing
8. severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
9. a return of fever or other signs of infection

Meropenem and vaborbactam injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

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