Melphalan Injection

• Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
• You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
• You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
• Talk with your doctor before getting any vaccines. Use with melphalan injection may either raise the chance of an infection or make the vaccine not work as well.
• If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
• To help with mouth sores, use a soft toothbrush or cotton swabs and rinse the mouth. Do not use mouth rinses that have alcohol in them.
• If you are 65 or older, use this medicine with care. You could have more side effects.
• This medicine may cause the ovaries to not work. This may also cause menstrual periods to stop. Talk with the doctor.
• This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. In both men and women, this may go back to normal but sometimes it may not. Talk with your doctor.
• If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for some time after care ends. Use birth control that you can trust. Talk with your doctor to see how long to use birth control after you stop melphalan injection.
• If you are a man and your sex partner gets pregnant while you take this medicine or within several months after your last dose, call your doctor right away.
• This medicine may cause harm to the unborn baby if you take it while you are pregnant.
• Use birth control that you can trust to prevent pregnancy during care and for some time after care ends. Talk with your doctor to see how long to use birth control after you stop melphalan injection.
• If you get pregnant while taking this medicine or within several months after the last dose, call your doctor right away.

Use melphalan injection as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• It is given as an infusion into a vein over a period of time.
• Other drugs may be given before this medicine to help avoid side effects.

What do I do if I miss a dose?

• Call your doctor to find out what to do.