Liothyronine Intravenous

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For liothyronine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to liothyronine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Limited information is available on the relationship of age to the effects of liothyronine injection in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of liothyronine in the elderly. However, elderly patients are more likely to have age-related kidney or heart and blood vessel problems, which may require adjustment of dosage in patients receiving liothyronine .

Pregnancy

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving liothyronine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using liothyronine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Midodrine

Using liothyronine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Kelp

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of liothyronine. Make sure you tell your doctor if you have any other medical problems, especially:

• Adrenal insufficiency (untreated) or
• Thyrotoxicosis (untreated; overactive thyroid)—liothyronine should NOT be used in patients with any of these conditions .

• Clotting disorder or
• Diabetes or
• Heart disease (history of) or
• Myxedema (skin or tissue disorder caused by hypothyroidism) or
• Other adrenal gland problems or
• Underactive pituitary gland—Use with caution. Dosage adjustment may be needed .

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Dizziness
• fainting
• fast, slow, or irregular heartbeat

• Bluish color
• blurred vision
• changes in skin color
• chest pain or discomfort
• chest tightness or heaviness
• confusion
• decreased urine output
• dilated neck veins
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• extreme fatigue
• fever
• headache
• heart stops
• irregular breathing
• nausea
• nervousness
• no breathing
• no pulse or blood pressure
• pain or discomfort in arms, jaw, back or neck
• pain, tenderness, swelling of foot or leg
• pounding in the ears
• shortness of breath
• sweating
• swelling of face, fingers, feet, or lower legs
• troubled breathing
• unconscious
• unusual tiredness or weakness
• vomiting
• weight gain
• wheezing

• Cold clammy skin
• increased bowel movements
• irritability
• lightheadedness
• menstrual changes
• shakiness in legs, arms, hands, feet
• trembling or shaking of hands or feet
• weak pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Twitching

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Consult your pharmacist.

How to use Liothyronine SODIUM Vial

Consult your pharmacist.

Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Consult your pharmacist.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.