Lidocaine and hydrocortisone Topical application, Rectal

In the U.S.

• AnaMantle HC
• Lida Mantle HC
• LidaMantle HC Relief
• LidoCort
• Peranex HC

Available Dosage Forms:

• Cream
• Pad
• Gel/Jelly
• Lotion

Therapeutic Class: Anesthetic Combination

Pharmacologic Class: Hydrocortisone

Chemical Class: Lidocaine

Lidocaine and hydrocortisone combination is used to relieve pain and itching caused by conditions such as hemorrhoids, sunburn, minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, minor cuts, or scratches.

Lidocaine belongs to a group of medicines known as topical local anesthetics. It deadens the nerve endings in the skin. lidocaine and hydrocortisone does not cause unconsciousness as general anesthetics do when used for surgery.

Hydrocortisone is a corticosteroid (cortisone-like medicine) that is used to relieve the redness, itching, and swelling caused by skin conditions.

lidocaine and hydrocortisone is available only with your doctor's prescription.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lidocaine and hydrocortisone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to lidocaine and hydrocortisone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of lidocaine and hydrocortisone combination in children. However, because of lidocaine and hydrocortisone's toxicity, it should be used with caution, after other medicines have been considered or found ineffective. Recommended doses should not be exceeded, and the patient should be carefully monitored during therapy.

Geriatric

No information is available on the relationship of age to the effects of lidocaine and hydrocortisone combination in geriatric patients. However, elderly patients are more likely to have age-related liver problems, which may require caution in patients receiving lidocaine and hydrocortisone combination.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking lidocaine and hydrocortisone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using lidocaine and hydrocortisone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amiodarone

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of lidocaine and hydrocortisone. Make sure you tell your doctor if you have any other medical problems, especially:

• Chickenpox infection or
• Fungal infection or
• Herpes simplex infection or
• Liver disease, severe or
• Tuberculosis, active—Should not be used in patients with these conditions.

• Cushing's syndrome (adrenal gland disorder) or
• Diabetes or
• Hyperglycemia (high blood sugar)—Use with caution. May make these conditions worse.

• Infection at or near the place of application or
• Large sores, broken skin, or severe injury at the area of application—The chance of side effects may be increased.

It is very important that your doctor check your progress at regular visits for any problems or unwanted effects that may be caused by lidocaine and hydrocortisone.

If your symptoms do not improve within a few days or if they become worse, check with your doctor.

Using too much of lidocaine and hydrocortisone or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and for patients who use large amounts for a long time. Talk to your doctor if you or your child have more than one of these symptoms while you are using lidocaine and hydrocortisone: blurred vision; dizziness or fainting; fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

After applying lidocaine and hydrocortisone to the skin of your child, watch the child carefully to make sure that he or she does not get any of the medicine in the eyes or mouth. lidocaine and hydrocortisone can cause serious side effects, especially in children, if it gets into the mouth and is swallowed.

Stop using lidocaine and hydrocortisone and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use cosmetics or other skin care products on the treated skin areas.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Burning or stinging sensation of the skin
• paleness or redness of the skin
• swelling of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.