K-Tab
Name: K-Tab
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K-Tab Overview
K-Tab is a prescription medication used to treat and prevent low potassium levels due to poor dietary intake, certain diseases, or other drugs. K-Tab belongs to a group of drugs called electrolytes, which are compounds that help the body function normally.
This medication comes in tablet form and may be taken multiple times a day with food and water.
Common side effects of K-Tab include nausea, vomiting, stomach discomfort or pain, and diarrhea.
Manufacturer
AbbVie Inc.
K-Tab Interactions
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- potassium-sparing diuretics such as amiloride (Midamor), triamterene (Dyrenium), and spironolactone (Aldactone)
- ACE inhibitors such as enalopril (Vasotec) and lisinopril (Prinivil, Zestril)
- vitamins containing potassium
This is not a complete list of K-Tab drug interactions. Ask your doctor or pharmacist for more information.
K-Tab Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of K-Tab, salt substitutes containing potassium should be avoided.
K-Tab and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
K-Tab falls into category C. This medication may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn baby.
It is not known if K-Tab will harm your unborn baby.
K-Tab Dosage
Take K-Tab exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
Dose amount is determined according to the individual needs of each patient:
- For the prevention of hypokalemia: typically in the range of 20 mEq per day
- For treatment of potassium depletion: typically in the range of 40-100 mEq per day or more
Dosage should be divided if more than 20 mEq per day. No more than 20 mEq is given in a single dose.
Proper Use of potassium supplement
This section provides information on the proper use of a number of products that contain potassium supplement. It may not be specific to K-Tab. Please read with care.
For patients taking the liquid form of this medicine:
- This medicine must be diluted in at least one-half glass (4 ounces) of cold water or juice to reduce its possible stomach-irritating or laxative effect.
- If you are on a salt (sodium)-restricted diet, check with your doctor before using tomato juice to dilute your medicine. Tomato juice has a high salt content.
For patients taking the soluble granule, soluble powder, or soluble tablet form of this medicine:
- This medicine must be completely dissolved in at least one-half glass (4 ounces) of cold water or juice to reduce its possible stomach-irritating or laxative effect.
- Allow any "fizzing" to stop before taking the dissolved medicine.
- If you are on a salt (sodium)-restricted diet, check with your doctor before using tomato juice to dilute your medicine. Tomato juice has a high salt content.
For patients taking the extended-release tablet form of this medicine:
- Swallow the tablets whole with a full (8-ounce) glass of water. Do not chew or suck on the tablet.
- Some tablets may be broken or crushed and sprinkled on applesauce or other soft food. However, check with your doctor or pharmacist first, since this should not be done for most tablets.
- If you have trouble swallowing tablets or if they seem to stick in your throat, check with your doctor. When this medicine is not properly released, it can cause irritation that may lead to ulcers.
For patients taking the extended-release capsule form of this medicine:
- Do not crush or chew the capsule. Swallow the capsule whole with a full (8-ounce) glass of water.
- Some capsules may be opened and the contents sprinkled on applesauce or other soft food. However, check with your doctor or pharmacist first, since this should not be done for most capsules.
Take this medicine immediately after meals or with food to lessen possible stomach upset or laxative action.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important if you are also taking both diuretics (water pills) and digitalis medicines for your heart.
Dosing
The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For potassium bicarbonate
- For oral dosage forms (tablets for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—25 to 50 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For potassium bicarbonate and potassium chloride
- For oral dosage form (granules for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For oral dosage form (tablets for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20, 25, or 50 mEq dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For potassium bicarbonate and potassium citrate
- For oral dosage form (tablets for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—25 or 50 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For potassium chloride
- For long-acting oral dosage form (extended-release capsules):
- To replace potassium lost by the body:
- Adults and teenagers—40 to 100 milliequivalents (mEq) a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- To prevent potassium loss:
- Adults and teenagers—16 to 24 mEq a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To replace potassium lost by the body:
- For long-acting oral dosage forms (liquid for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 mEq mixed into one-half glass of cold water or juice, taken one to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq of potassium per kilogram (kg) (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed in water or juice.
- To prevent potassium loss or replace potassium lost by the body:
- For oral dosage form (powder for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—15 to 25 mEq dissolved in four to six ounces of cold water, taken two or four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq per kg (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be mixed into water or juice.
- To prevent potassium loss or replace potassium lost by the body:
- For oral dosage form (powder for suspension):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 mEq dissolved in two to six ounces of cold water, taken one to five times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For long-acting oral dosage form (extended-release tablets):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—6.7 to 20 mEq taken three times a day. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For oral dosage form (liquid for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight a day, taken in smaller doses during the day. The solution should be completely mixed into water or juice.
- To prevent potassium loss or replace potassium lost by the body:
- For oral dosage form (tablets):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—5 to 10 mEq taken two to four times a day. However, most people will not take more than 100 mEq a day.
- Children—Dose must be determined by your doctor.
- To prevent potassium loss or replace potassium lost by the body:
- For potassium gluconate and potassium chloride
- For oral dosage form (liquid for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 milliequivalents (mEq) diluted in 2 tablespoonfuls or more of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
- To prevent potassium loss or replace potassium lost by the body:
- For oral dosage form (powder for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 mEq mixed in 2 tablespoonfuls or more of cold water or juice taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is base on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
- To prevent potassium loss or replace potassium lost by the body:
- For potassium gluconate and potassium citrate
- For oral dosage form (liquid for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
- To prevent potassium loss or replace potassium lost by the body:
- For trikates
- For oral dosage form (liquid for solution):
- To prevent potassium loss or replace potassium lost by the body:
- Adults and teenagers—15 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken three or four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
- Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
- To prevent potassium loss or replace potassium lost by the body:
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Keep out of the reach of children.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not keep outdated medicine or medicine no longer needed.
K-Tab - Clinical Pharmacology
Potassium ion is the principal intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, and the maintenance of normal renal function.
The intracellular concentration of potassium is approximately 150 to 160 mEq per liter. The normal adult plasma concentration is 3.5 to 5 mEq per liter. An active ion transport system maintains this gradient across the plasma membrane.
Potassium is a normal dietary constituent and under steady state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. The usual dietary intake of potassium is 50 to 100 mEq per day.
Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Such depletion usually develops as a consequence of therapy with diuretics, primary or secondary hyperaldosteronism, diabetic ketoacidosis, or inadequate replacement of potassium in patients on prolonged parenteral nutrition. Depletion can develop rapidly with severe diarrhea, especially if associated with vomiting. Potassium depletion due to these causes is usually accompanied by a concomitant loss of chloride and is manifested by hypokalemia and metabolic alkalosis. Potassium depletion may produce weakness, fatigue, disturbances of cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and, in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine.
If potassium depletion associated with metabolic alkalosis cannot be managed by correcting the fundamental cause of the deficiency, e.g., where the patient requires long term diuretic therapy, supplemental potassium in the form of high potassium food or potassium chloride may restore normal potassium levels.
In rare circumstances, (e.g., patients with renal tubular acidosis) potassium depletion may be associated with metabolic acidosis and hyperchloremia. In such patients potassium replacement should be accomplished with potassium salts other than the chloride, such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate.
For the Consumer
Applies to potassium chloride: oral tablet extended release
Other dosage forms:
- oral capsule extended release
- intravenous solution
- oral packet, oral solution
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a high potassium level like a heartbeat that does not feel normal; change in thinking clearly and with logic; feeling weak, lightheaded, or dizzy; feel like passing out; numbness or tingling; or shortness of breath.
- Slow heartbeat.
- Chest pain or pressure.
- Very hard stools (constipation).
- Very upset stomach or throwing up.
- Swelling of belly.
- Black, tarry, or bloody stools.
- Throwing up blood or throw up that looks like coffee grounds.
- Very bad belly pain.