Florbetapir (18F)

Florbetapir (18F) is a diagnostic agent used during imaging of the brain to estimate plaque density in patients who are being evaluated for Alzheimer’s Disease (AD).

Florbetapir (18F) belongs to a group of drugs called radioactive diagnostic agent. This medication works by binding to the plaque in the brain in order to be detected during imaging of the brain.

This medication is available in an injectable form to be given directly into a vein (IV) by a healthcare professional.

Common side effects of florbetapir (18F) include headache, muscle pain, and an increase in blood pressure.

florbetapir (18F) is part of the drug class:

• Other central nervous system diagnostic radiopharmaceuticals

Common side effects of florbetapir (18F) include the following:

• Headache
• Musculoskeletal pain
• Blood Pressure Increase
• Nausea

This is not a complete list of florbetapir (18F) side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away. 

No drug interactions have been studied by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported. 

Florbetapir (18F), similar to other radiopharmaceuticals, contributes to a patients overall long-term cumulative radiation exposure. Long-term cumulative radiation exposure is associated with an increased risk of cancer.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Florbetapir (18F) falls into category C. No well-controlled studies have been done in animals. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

All radiopharmaceuticals, including florbetapir (18F), have a potential to cause harm to your unborn baby. The likelihood of harm to your unborn baby will depends on the stage of fetal development and the dose of florbetapir (18F).