Ethiodized oil Injection

In the U.S.

• Ethiodol
• Lipiodol3

Available Dosage Forms:

• Injectable
• Solution

Therapeutic Class: Radiological Non-Ionic Contrast Media

Ethiodized oil injection is an oil-based radiopaque contrast agent. Contrast agents are used to help create a clear picture of the body during different medical procedures. These include:

• Hysterosalpingography (x-ray test that looks inside the uterus and fallopian tubes) in adults
• Lymphography (x-ray test that looks at the lymph vessels of the feet or hands) in adults and children
• Imaging of liver tumors in adults.

ethiodized oil is to be given only by or under the direct supervision of your doctor.

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ethiodized oil or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ethiodized oil injection for lymphography in children.

Geriatric

Appropriate studies on the relationship of age to the effects of ethiodized oil injection have not been performed in the geriatric population. However, no geriatric-specific problems have been documented to date.

Pregnancy

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this diagnostic test, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this diagnostic test with any of the following medicines is not recommended. Your doctor may decide not to use this diagnostic test or change some of the other medicines you take.

• Metformin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to iodinated contrast agents or
• Asthma—May increase risk of having an allergic reaction to occur again.

• Bleeding in the uterus or
• Curettage or conization with 30 days or
• Cervical erosion or
• Endocervicitis (inflammation of the cervix) or
• Immediate premenstrual or postmenstrual time frame or
• Pelvic inflammatory disease
• Pregnant—Patients with these conditions should not receive Lipiodol® for hysterosalpingography.

• Bleeding, recent or
• Hyperthyroidism (overactive thyroid) or
• Trauma—Should not be used in patients with these conditions.

• Dilated bile ducts without external drainage—Patients with this condition should not receive Lipiodol® for liver tumor imaging.

• Heart disease or
• Liver disease or
• Lung disease or
• Portal hypertension (high blood pressure in the liver portal vein) or
• Thyroid problems—Use with caution. May make these conditions worse.

• Advanced lung disease or
• Advanced neoplastic disease with expected lymphatic obstruction or
• Radiation therapy to the examined area or
• Right-to-left cardiac shunt or
• Surgery interrupting the lymphatic system, recent—Patients with this condition should not receive Lipiodol® for lymphography.

Your doctor will check your progress closely while you are receiving ethiodized oil. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects.

ethiodized oil may cause pulmonary embolism (blood clots in the lungs). Tell your doctor right away if you have anxiety, chest pain, cough, dizziness or lightheadedness, fainting, fast heartbeat, sudden shortness of breath, or troubled breathing.

ethiodized oil may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are receiving ethiodized oil.

Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Missed Dose

Consult your pharmacist.

Storage

Consult your pharmacist.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised July 2016. Copyright(c) 2016 First Databank, Inc.