Empagliflozin Oral Tablet

Name: Empagliflozin Oral Tablet

Highlights for empagliflozin

Empagliflozin is used along with diet and exercise to help lower blood sugar levels in adults with type 2 diabetes. It’s also used to reduce the risk of death from cardiovascular problems in people with type 2 diabetes and cardiovascular disease.

Empagliflozin works in your kidneys to remove sugar from your blood and moves the sugar into your urine. 

The most common side effect that occurs with empagliflozin is a urinary tract infection. Symptoms include a burning sensation when urinating, cloudy urine, or pain in your pelvis or back.

This medication can increase your cholesterol levels. If you already have high cholesterol, your doctor will monitor your cholesterol closely and treat it if necessary. 

If you take empagliflozin with other diabetes medications, your blood sugar might get too low (hypoglycemia). Symptoms may include shakiness, confusion, sweating, rapid heartbeat, nervousness, headache, weakness, or fatigue. Contact your doctor if you experience these symptoms.

IMPORTANT INFORMATION
  • Dehydration See Details

  • Yeast infection See Details

  • Ketoacidosis See Details

  • Urinary tract infections See Details

What is empagliflozin?

This drug is a prescription drug. It’s available as an oral tablet.

This drug may be used as part of a combination therapy. That means you need to take it with other drugs.

Why it's used

This drug is used to treat type 2 diabetes along with diet and exercise to help lower blood sugar in adults.

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How it works

This drug belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2).

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Empagliflozin Side Effects

Most Common Side Effects

The most common side effect that occurs with empagliflozin is:

  • urinary tract infection. Symptoms may include:

    • a burning sensation when you urinate
    • cloudy urine
    • pain in your pelvis or back

Your doctor will need to treat you if you have a urinary tract infection. If you continue to use empagliflozin, these symptoms may come back.

Serious Side Effects

If you experience any of these serious side effects, call your doctor right away. If your symptoms are potentially life threatening, or if you think you’re experiencing a medical emergency, call 9-1-1.

  • dehydration. Symptoms may include:

    • dizziness
    • feeling faint
    • lightheadedness
    • weakness, especially when you stand up
  • yeast infection. Symptoms in women may include:

    • vaginal odor
    • white or yellowish vaginal discharge
    • vaginal itching

    Symptoms in men may include:

    • redness, itching, or swelling of the penis
    • rash of the penis
    • foul-smelling discharge from the penis
    • pain in the skin around the penis
  • low blood sugar (hypoglycemia). Symptoms may include:

    • drowsiness
    • headache
    • confusion
    • weakness
    • hunger
    • irritability
    • sweating
    • feeling jittery
    • fast heartbeat
  • allergic reactions. Symptoms may include:

    • swelling of your face, throat, lips, and other areas on your skin
    • difficulty swallowing or breathing
    • raised, red areas on your skin (hives)
    • skin rash
  • kidney damage. Symptoms may include:

    • weakness
    • tiredness
    • more frequent urination
    • swollen ankles and feet
    • muscle cramps
  • increased cholesterol levels

  • diabetic ketoacidosis. Symptoms can include:

    • excessive thirst
    • urinating more often than normal
    • nausea
    • vomiting
    • stomach pain
    • weakness
    • shortness of breath
    • fruity smelling breath
    • confusion
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Empagliflozin May Interact with Other Medications

Empagliflozin can interact with other medications, herbs, or vitamins you might be taking. That’s why your doctor should manage all of your medications carefully. If you’re curious about how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Note: You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. That way, a pharmacist can check for possible drug interactions.

Alcohol Interactions

Limit your use of alcohol. Drinking alcohol can lower your blood glucose control and increase your risk of hypoglycemia if you take medication for diabetes.

Medications That Might Interact with This Drug

Drugs for water retention (diuretics)
  • hydrochlorothiazide
  • furosemide

These drugs increase urination. Empagliflozin can also increase urination, so taking these drugs together can increase your risk of dehydration.

Insulin or drugs that cause the release of insulin
  • chlorpropamide
  • glipizide
  • glimepiride
  • glyburide
  • tolbutamide
  • tolazamide
  • repaglinide
  • nateglinide

Empagliflozin and these drugs all decrease your blood sugar level. Taking empagliflozin with these drugs could cause your blood sugar level to be too low (hypoglycemia). 

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Drug warnings

People with high cholesterol

This medication can increase your cholesterol levels. If you already have high cholesterol, your doctor will monitor your cholesterol closely and treat it if necessary.

People with kidney problems

This drug can cause kidney damage. If you already have kidney problems, your doctor may not prescribe this drug for you.

Pregnant women

This drug is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Speak with your doctor if you’re pregnant or planning to become pregnant. Empagliflozin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Women who are breast-feeding

It isn’t known if this drug passes through breast milk. You and your doctor should decide if you’ll take this drug or breastfeed. 

For children

The safety and effectiveness of this drug in children haven’t been established.

Allergies

This drug can cause a severe allergic reaction, causing symptoms such as:

  • trouble breathing
  • swelling of your throat or tongue
  • hives 

Don’t take this drug again if you’ve ever had an allergic reaction to empagliflozin or any other ingredient. Taking it again could be fatal.

How to Take empagliflozin (Dosage)

All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What Are You Taking This Medication For?

Type 2 diabetes Form: Oral tablet Strengths: 10 mg and 25 mg Adult Dosage (ages 18 years and older)
  • Initial dose is 10 mg, taken once per day in the morning.
  • Doses may be increased up to 25 mg, taken once per day in the morning.
Child Dosage (ages 0-17 years)

Dosage for people younger than 18 years old hasn’t been established.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you. Important considerations for taking this drug

Take it in the morning

You can cut or crush the tablet

Store this drug from 68–77°F (20–25ºC)

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Prescription is refillable

Travel

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Clinical monitoring

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Not every pharmacy stocks this drug, so call ahead

Insurance

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Are there any alternatives?

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