Burosumab-twza Injection

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Unless your doctor tells you otherwise, continue your normal diet.

Burosumab-twza injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache
• vomiting
• fever
• pain in arms, legs, or back
• muscle pain
• constipation
• dizziness

Some side effects can be serious. If you experience any of these symptoms, call your doctor:

• redness, rash, hives, itching, swelling, pain, or bruising near or at the spot that the medication was injected
• rash or hives
• discomfort in the legs; a strong urge to move the legs, especially at night and when sitting or lying down

Burosumab-twza injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before and during your treatment to check your body's response to burosumab-twza injection.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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