Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine

Brompheniramine, chlorpheniramine, and methscopolamine are antihistamines that reduce the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine and pseudoephedrine are decongestants that shrink blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

This combination medicine may also be used for purposes not listed in this medication guide.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Ask a doctor or pharmacist before using any other cold, allergy, cough, or sleep medicine. Many combination medicines contain antihistamines or decongestants. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine or decongestant.

Drinking alcohol with this medicine can cause side effects.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medication can decrease sweating and you may be more prone to heat stroke.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• pounding heartbeats or fluttering in your chest;

• shortness of breath;

• mood changes;

• tremor, seizure (convulsions);

• double vision;

• ongoing diarrhea or vomiting;

• little or no urination;

• easy bruising or bleeding, unusual weakness; or

• high blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects may include:

• headache, dizziness, drowsiness;

• dry mouth, nose, or throat;

• tingly feeling;

• nausea, bloating, constipation;

• blurred vision;

• feeling nervous or restless;

• sleep problems (insomnia); or

• decreased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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