Asenapine (Sublingual Route)

Name: Asenapine (Sublingual Route)

US Brand Name

  1. Saphris

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Blood vessel or circulation problems or
  • Dehydration or
  • Heart attack, history of or
  • Heart disease or
  • Heart failure or
  • Heart rhythm problems (eg, arrhythmia, QT prolongation) or
  • Hypotension (low blood pressure) or
  • Hypovolemia (low amount of blood) or
  • Stroke, history of—May cause side effects to become worse.
  • Bradycardia (slow heartbeat), history of or
  • Heart rhythm problem (eg, congenital long QT syndrome) or
  • Hypokalemia (low potassium in the blood) or
  • Hypomagnesemia (low magnesium in the blood)—May increase risk for more serious side effects.
  • Diabetes or
  • Hyperglycemia (high blood sugar)—This medicine may raise your blood sugar levels.
  • Hyperprolactinemia (high prolactin in the blood) or
  • Neuroleptic malignant syndrome (NMS), history of or
  • Seizures, history of or
  • Trouble with swallowing—Use with caution. May make these conditions worse.
  • Liver disease, severe—Should not be used in patients with this condition.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

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