Artemether Lumefantrine Tablets

You should not use this medication if you are allergic to artemether or lumefantrine.

Many drugs can interact with artemether and lumefantrine and some should not be used at the same time. Tell your doctor about all other medications you use.

Before using this medication, tell your doctor if you have a history of heart disease or recent heart attack, a heart rhythm disorder (especially '"Long QT syndrome), liver or kidney disease, or low levels of potassium or magnesium in your blood.

Take artemether and lumefantrine with food, milk, pudding, oatmeal, or broth. The tablet may be crushed and mixed with water for easier swallowing.

If you vomit within 1 to 2 hours after taking this medication, take another dose. If your vomiting continues or you cannot eat, call your doctor.

You should not use this medication if you are allergic to artemether or lumefantrine.

Many drugs can interact with artemether and lumefantrine and some should not be used at the same time. Tell your doctor about all other medications you use, especially:

• bosentan (Tracleer);
• dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
• halofantrine (Halfan) taken within the past 30 days;
• St. John's wort;
• rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
• a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
• HIV/AIDS medication such as efavirenz (Sustiva, Atripla), etravirine (Intelence), nevirapine (Viramune), or ritonavir (Norvir, Kaletra);
• medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil); or
• seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).

To make sure artemether and lumefantrine is safe for you, tell your doctor if you have any of these other conditions:

• a history of heart disease or a recent heart attack;
• heart rhythm disorder, or a personal or family history of Long QT syndrome;
• liver or kidney disease; or
• low levels of potassium or magnesium in your blood.

FDA pregnancy category C. It is not known whether artemether and lumefantrine is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Use a barrier form of birth control (such as a condom or diaphragm with spermicide). Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment.

It is not known whether artemether and lumefantrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artemether and lumefantrine should not be given to a child who weighs less than 11 pounds.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.