Anascorp Injection
Name: Anascorp Injection
- Anascorp Injection drug
- Anascorp Injection injection
- Anascorp Injection mg
- Anascorp Injection action
Drug Interactions
No drug interaction studies have been conducted with Anascorp.
Anascorp Injection - Clinical Pharmacology
Mechanism of Action
Anascorp is a venom-specific F(ab')2 fragments of immunoglobulin G (IgG) that bind and neutralize venom toxins, facilitating redistribution away from target tissues and elimination from the body.1
Pharmacokinetics
Eight clinically healthy volunteers (6 males and 2 females, age: 17 to 26 years) received a bolus intravenous dose of 47.5 mg of Centruroides (Scorpion) Immune F(ab’)2, (Equine) Injection. Blood samples were collected till 504 hours (21 days) and pharmacokinetic parameters were estimated by non-compartmental analysis which are summarized in Table 2.
| Parameters | Mean ± sd |
| AUC(0-∞)(µg•hr/mL) | 706 ± 352 |
| Clearance (mL/hr) | 83.5 ± 38.4 |
| Half-life (hrs) | 159 ± 57 |
| Vss (liters) | 13.6 ± 5.4 |