Alti-Pindolol

In the U.S.

• Visken

In Canada

• Alti-Pindolol

Available Dosage Forms:

• Tablet

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Beta-Adrenergic Blocker, Nonselective

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Swelling of the face, fingers, feet, or lower legs

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest pain
• difficult or labored breathing
• shortness of breath
• tightness in chest
• wheezing

• Decreased urine output
• dilated neck veins
• extreme fatigue
• fast, irregular, pounding, or racing heartbeat or pulse
• irregular breathing
• seeing, hearing, or feeling things that are not there
• troubled breathing
• weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

• Blurred vision
• dizziness
• headache
• nervousness
• pounding in the ears
• slow heartbeat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Joint pain
• muscle pain
• sleeplessness
• trouble sleeping
• unable to sleep
• unusual tiredness or weakness

• Itching skin
• muscle cramps
• nausea
• stomach soreness or discomfort
• unusual dreams
• weakness

• Rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Applies to pindolol: oral tablet

Along with its needed effects, pindolol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking pindolol:

• Swelling of the face, fingers, feet, or lower legs

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest pain
• difficult or labored breathing
• shortness of breath
• tightness in chest
• wheezing

• Decreased urine output
• dilated neck veins
• extreme fatigue
• fast, irregular, pounding, or racing heartbeat or pulse
• irregular breathing
• seeing, hearing, or feeling things that are not there
• troubled breathing
• weight gain

Get emergency help immediately if any of the following symptoms of overdose occur while taking pindolol:

• Blurred vision
• dizziness
• headache
• nervousness
• pounding in the ears
• slow heartbeat

Some side effects of pindolol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Joint pain
• muscle pain
• sleeplessness
• trouble sleeping
• unable to sleep
• unusual tiredness or weakness

• Itching skin
• muscle cramps
• nausea
• stomach soreness or discomfort
• unusual dreams
• weakness

• Rash

Applies to pindolol: compounding powder, oral tablet

Cardiovascular

Common (1% to 10%): Edema
Uncommon (0.1% to 1%): Heart failure, palpitations
Frequency not reported: Bradycardia, slowed AV-conduction or increase of an existing AV-block, hypotension, heart failure, cold and cyanotic extremities, Raynaud's phenomenon, increase in intermittent claudication, conduction disorder, cardiac arrhythmia[Ref]

Endocrine

Frequency not reported: Hypoglycemia[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, abdominal discomfort
Frequency not reported: Vomiting, diarrhea[Ref]

Genitourinary

Uncommon (0.1% to 1%): Male impotence[Ref]

Musculoskeletal

Very common (10% or more): Muscle pain (10%)
Common (1% to 10%): Chest pain, joint pain, muscle cramps[Ref]

Nervous system

Very common (10% or more): Dizziness (up to 11%)
Common (1% to 10%): Paresthesia
Frequency not reported: Headache
Postmarketing reports: Tremor[Ref]

Respiratory

Common (1% to 10%): Dyspnea
Postmarketing reports: Bronchospasm[Ref]

Dermatologic

Common (1% to 10%): Pruritus
Uncommon (0.1% to 1%): Rash
Frequency not reported: Hyperhidrosis, worsening of psoriasis, erythematous rashes[Ref]

Ocular

Frequency not reported: Impaired vision, dry eyes, keratitis, conjunctivitis[Ref]

Other

Common (1% to 10%): Fatigue, weakness[Ref]

Psychiatric

Very common (10% or more): Insomnia (10%)
Common (1% to 10%): Nightmares
Uncommon (0.1% to 1%): Hallucinations
Frequency not reported: Psychosis, confusion, sleep disturbance, depression[Ref]

Some side effects of pindolol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Data not available

Administration advice:
-This drug may be taken with or without food.

General:
-This drug may be given alone or in combination with other antihypertensive drugs.
-Antihypertensive response usually occurs within the first week of treatment.
-Maximal response may take 2 weeks or longer.

Monitoring:
-Both cardiac and thyroid function should be monitored in patients having, or suspected of developing, thyrotoxicosis.

UK: Use is contraindicated. AU, US: This drug should be used during pregnancy only if the benefit outweighs the risk. AU TGA pregnancy category: C US FDA pregnancy category: B Comment: -Beta adrenergic blocking agents may cause bradycardia in the fetus.

Animal studies exceeding 100 times the maximum recommended human doses, revealed no embryotoxicity or teratogenicity. There are no controlled data in human pregnancy. It is not known whether this drug can cause fetal harm or adversely affect reproductive capacity in humans. AU TGA pregnancy category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible. Accompanying texts should be consulted for further details. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

LactMed Record Number

300

Last Revision Date

20140116

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.