Name: A-Spaz

Uses of A-Spaz

  • It is used to slow the speed in the stomach and GI (gastrointestinal) tract.
  • It is used to treat loose stools (diarrhea).
  • It is used to treat GI (gastrointestinal) ulcers.
  • It is used to treat irritable bowel syndrome.
  • It is used to treat muscle spasms of the GI (gastrointestinal) tract, gallbladder system, or urinary system.
  • It is used to treat a runny nose.
  • It is used to treat Parkinson's disease.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take A-Spaz?

  • If you have an allergy to hyoscyamine or any other part of A-Spaz (hyoscyamine sublingual tablets).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Bowel block, bleeding problems, diarrhea, enlarged colon, glaucoma, heart problems, myasthenia gravis, slow-moving GI (gastrointestinal) tract, a swallowing tube (esophagus) that is not normal, ulcerative colitis, or trouble passing urine.
  • If you are breast-feeding or plan to breast-feed.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take A-Spaz with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take A-Spaz?

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how A-Spaz affects you.
  • Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
  • Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
  • Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help with dry mouth. See a dentist often.
  • If you are 65 or older, use this medicine with care. You could have more side effects.
  • Different brands of A-Spaz may be for use in different ages of children. Talk with the doctor before giving this medicine to a child.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using A-Spaz while you are pregnant.

What are some other side effects of A-Spaz?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling sleepy.
  • Dizziness.
  • Blurred eyesight.
  • Hard stools (constipation).
  • Dry mouth.
  • Dry eyes.
  • Headache.
  • Upset stomach or throwing up.
  • Stomach pain.
  • Change in taste.
  • Feeling nervous and excitable.
  • Feeling tired or weak.
  • Feeling full.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Usual Adult Dose for Endoscopy or Radiology Premedication

0.25 to 0.5 mg (0.5 to 1 mL) IV 5 to 10 minutes prior to the diagnostic procedure.

Oral Spray:
Endoscopic retrograde cholangiopancreatography: 2 sprays (0.25 mg) 20 minutes prior to the procedure.

Liver Dose Adjustments

Data not available


As with other anticholinergic agents, hyoscyamine is contraindicated for patients with angle-closure glaucoma, and should be used cautiously in patients with pyloric or suspected intestinal obstruction or urinary bladder neck obstruction, and in patients with myasthenia gravis.

Use with caution in patients with hiatal hernia associated with reflux esophagitis.

Caution should be exercised when using hyoscyamine in patients with: autonomic neuropathy, hyperthyroidism, coronary heart disease, congestive heart failure, cardiac arrhythmias, hypertension and renal disease.

Hyoscyamine may cause drowsiness, confusion, and disorientation. The elderly and the renally or hepatically impaired may be particularly sensitive to these effects. All patients should be cautioned against engaging in activities which require mental alertness, such as driving or operating dangerous machinery, while using hyoscyamine. The concomitant use of alcohol or other agents possessing CNS depressant activity should be avoided if possible.

Anticholinergics may increase the heart rate, for this reason the occurrence of tachycardia should be closely evaluated before giving hyoscyamine.


Data not available